Reality: Serious liver or kidney problems from statins are very uncommon. Today,experts agree that statins are safe even in people with fatty liver disease or compensated cirrhosis, and they shouldn’t be withheld when heart benefits are expected. For kidneys, randomized evidence shows no clear increase in acute kidney injury with regular statin use. In fact, guidelines recommend them for most people with chronic kidney disease (except those on dialysis), since their cardiovascular risk is higher. However, a large observational study linked high-dose rosuvastatin to small increases in hematuria or proteinuria, especially in advanced CKD. That’s why careful dosing is important in such patients.